Source data for EU Drug Market: EU Drug Market: New psychoactive substances — In-depth analysis

This data bundle contains all data tables and source data used in graphics in the publication: EU Drug Market: New psychoactive substances — In-depth analysis

List of tables

Number of laboratory sites associated with NPS production dismantled in Europe in 2013-2016
Country Number of laboratory sites
Belgium 1
Bulgaria 1
Czechia 2
Estonia 2
France 0
Germany 2
Hungary 1
Netherlands 16
Poland 9
Romania 5
Slovakia 2
Spain 1
Sweden 4
Number of laboratory sites associated with NPS production dismantled in Europe in 2017-2021
Country Number of laboratory sites
Belgium 4
Bulgaria 0
Czechia 0
Estonia 0
France 1
Germany 11
Hungary 0
Netherlands 52
Poland 37
Romania 1
Slovakia 1
Spain 2
Sweden 1
Number of laboratory sites associated with NPS production dismantled in Europe in 2017-2021, by category of new psychoactive substance produced
Category 2017 2018 2019 2020 2021 Total
Arylalkylamines 0 1 0 0 0 1
Ketamine 1 0 1 1 1 4
Cannabinoids 0 3 1 1 0 5
Cathinones 8 3 5 14 17 47
Indolalkylamines 0 1 1 0 0 2
Opioids 1 2 1 0 0 4
GHB/GBL 4 8 8 9 5 34
Phenethylamines 1 3 1 0 0 5
Unspecified NPS 0 4 7 2 2 15
Number of new psychoactive substances notified to the EU Early Warning System for the first time, European Union, 2005-2023
Years Number of NPS
2005 13
2006 7
2007 14
2008 13
2009 21
2010 41
2011 48
2012 74
2013 81
2014 101
2015 98
2016 66
2017 51
2018 55
2019 53
2020 46
2021 52
2022 41
2023 26
Number of new psychoactive substances notified to the EU Early Warning System for the first time by category, European Union, 2005–2023
Year Aminoindanes Arylalkylamines Arylcyclohexylamines Benzodiazepines Cannabinoids Cathinones Opioids Other substances Phenethylamines Piperazines Piperidines and pyrrolidines Plants and extracts Tryptamines
2005   1       1     3 2     6
2006 1 1             2 3      
2007   2   1         3 2 1 3 2
2008         1 6   1 1     3 1
2009         6 4 1 2 5   1   2
2010 1 3 2   11 14   3 3 1 1 1 1
2011 1 5 1 1 23 7   4 4   2    
2012   5 3 1 31 4 3 8 14 1     4
2013 1 6 1 2 29 8 4 13 14 1 1   1
2014   4   4 30 31 4 14 9       5
2015   4 2 5 24 26 4 12 9 3 6   3
2016   3 6 6 11 14 9 10 5   1   1
2017   1 1 3 10 12 13 4 4   1   2
2018   1 1 5 11 8 11 9 5       4
2019   1   2 8 10 8 13 3 2 1   5
2020 1 4 3   11 8 10 4         5
2021     5 3 15 6 6 9 4       4
2022   1 2 2 24 5 1 3 1 1     1
2023       1 9 3 7 2 4        
Numbers and categories of new psychoactive substances detected each year following their first identification, European Union, 2005-2022
Year Aminoindanes Arylalkylamines Arylcyclohexylamines Benzodiazepines Cannabinoids Cathinones Tryptamines Opioids Other substances Phenethylamines Piperazines Piperidines and Pyrrolidines
2005 0 1 1 1 0 1 13 0 4 8 3 0
2006 1 3 2 1 0 0 8 0 3 10 4 0
2007 1 2 1 1 0 2 16 0 5 12 8 1
2008 0 2 2 1 2 7 9 0 7 11 6 1
2009 2 2 2 1 6 10 11 1 8 16 6 2
2010 1 3 3 1 16 22 15 1 5 21 9 2
2011 3 6 4 1 41 30 16 1 10 31 7 3
2012 3 14 7 3 55 37 20 5 15 35 7 4
2013 4 19 7 5 63 45 17 7 28 47 8 5
2014 4 19 7 10 86 70 19 9 37 49 9 4
2015 4 20 8 12 93 88 22 12 41 50 10 9
2016 4 22 12 19 89 96 20 17 42 45 9 11
2017 4 19 13 26 84 93 29 30 42 47 6 13
2018 3 18 10 22 90 93 28 29 48 44 8 10
2019 4 16 12 18 81 90 27 26 63 47 8 10
2020 2 13 17 20 77 78 23 29 47 36 4 11
2021 3 16 19 18 100 78 25 28 56 39 6 8
2022 4 18 17 23 86 78 25 20 55 40 10 8
Seizures of new psychoactive substances reported to the EU Early Warning System: total number of seizures, European Union, 2005-2022
Year 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Number of seizures 929 1301 1857 3264 5996 6475 7891 11410 25208 24154 34190 46019 37583 33618 22450 21252 29399 26390
Seizures of new psychoactive substances reported to the EU Early Warning System: quantity of material seized for all forms reported in weight, European Union, 2005-2022
Year 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Quantity seized (kg) 1.896 22.601 65.771 62.241 944.083 1110.328 676.245 1805.11 1940.076 2925.087 4599.363 3175.676 3018.483 4118.687 2042.919 5134.434 8527.035 30681.746
Seizures of new psychoactive substances reported to the EU Early Warning System: total number of seizures by category, European Union, 2022
Category Number of seizures
Cathinones 9661
Cannabinoids 4683
Others 4451
Arylcyclohexylamines 3920
Phenethylamines 1337
Benzodiazepines 752
Opioids 749
Arylalkylamines 423
Tryptamines 213
Piperidines and pyrrolidines 105
Piperazine derivates 86
Aminoindanes 10
Seizures of new psychoactive substances reported to the EU Early Warning System: total number of seizures by category substance, European Union, 2022
Substance Number of seizures
Ketamine 3462
3-CMC 2997
Pregabalin 2339
4-CMC 1962
ADB-BUTINACA 1645
3-MMC 1204
2C-B 901
alpha-PHP 674
MDMB-4en-PINACA 575
N-ethylnorpentedrone 571
Other 10060
Seizures of new psychoactive substances reported to the EU Early Warning System: quantity of material seized by category for all forms reported in weight, European Union, 2022
Category Quantity material (kg)
Cathinones 26522.926
Cannabinoids 844.026
Others 375.732
Arylcyclohexylamines 2798.233
Phenethylamines 53.821
Benzodiazepines 4.203
Opioids 16.594
Arylalkylamines 59.022
Tryptamines 4.404
Piperidines and pyrrolidines 2.538
Piperazine derivates 0.194
Aminoindanes 0.051
Seizures of new psychoactive substances reported to the EU Early Warning System: quantity of material seized by substance for all forms reported in weight, European Union, 2022
Substance Quantity material (kg)
3-CMC 19414.919
3-MMC 2848.907
Ketamine 2792.879
2-MMC 1510.029
N-ethylnorpentedrone 1056.867
alpha-PHiP 568.344
JWH-210 467.506
Eutylone 334.37
MDPHP 179.661
Mephedrone 167.267
Other 1340.997
Seizures of new psychoactive substances reported to the EU Early Warning System by country: numbers of seizures, European Union, 2022
Country Number of seizures
Austria 141
Belgium  
Bulgaria 996
Cyprus 12
Czechia 47
Germany 2418
Denmark 173
Estonia 323
Greece 86
Spain 5444
Finland 1602
France 2572
Croatia 25
Hungary 1415
Ireland 6
Italy 142
Lithuania 564
Luxembourg 50
Latvia 409
Malta 5
Netherlands 1056
Poland 3760
Portugal 257
Romania 10
Sweden 4717
Slovenia 133
Slovakia 27
Seizures of new psychoactive substances reported to the EU Early Warning System by country: quantity of material seized for all forms reported in weight, European Union, 2022
Country Quantity material (kg)
Austrial 20.179
Belgium 0
Bulgaria 14.956
Cyprus 0.01
Czechia 4.139
Germany 199.249
Denmark 501.604
Estonia 169.703
Greece 12.951
Spain 4005.083
Finland 47.22
France 0
Croatia 2.478
Hungary 158.369
Ireland 0.012
Italy 56.04
Lithuania 16.531
Luxembourg 0.141
Latvia 84.47
Malta 0.016
Netherlands 24612.796
Poland 305.978
Portugal 20.321
Romania 1.66
Sweden 442.325
Slovenia 5.263
Slovakia 0.255
Dismantled laboratories associated with cathinone production in Europe by substance produced, 2017-2021
Cathinone produced Number of laboratories
3-CMC 5
3-MMC 1
4-CMC 17
alpha-PHP 1
4-MMC 23
Seizures of cathinone precursors in Europe by cathinone produced, 2017-2021
Cathinone precursor used 2-CMC 4-CMC 4-MMC Other cathinones x-MMC
2017 110   1211.265    
2018   500 50.077    
2019   305.991 12.824   120
2020   407.3 445.2 50  
2021   20 244 291.4  
Number of synthetic cathinones notified to the EU Early Warning System for the first time, European Union, 2005-2023
Row Labels Cathinones
2005 1
2008 6
2009 4
2010 14
2011 7
2012 4
2013 8
2014 31
2015 26
2016 14
2017 12
2018 8
2019 10
2020 8
2021 6
2022 5
2023 3
Seizures of synthetic cathinones reported to the EU Early Warning System: trends in total number of seizures, European Union, 2005-2022
Year 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Number of seizures 6   7 161 1010 1790 2662 2988 6398 6273 12398 21945 15061 13906 6413 5503 8449 9661
Seizures of synthetic cathinones reported to the EU Early Warning System: quantity of material seized for all forms reported in weight, European Union, 2005-2022
Year 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Quantity seized (kg) 0.5 0 0 7 49.5 402.3 394.7 840.6 894.5 992.3 1786.9 1909.9 1160.4 1070.6 752.9 3307.6 4536.6 26522.9
Top five synthetic cathinones seized by number of seizures reported to the EU Early Warning System, European Union, 2022
Substance Number of seizures
3-CMC 2997
4-CMC 1962
3-MMC 1204
alpha-PHP 674
N-ethylnorpentedrone 571
Other 2253
Top five synthetic cathinones seized by quantity of material seized for all forms reported in weight reported to the EU Early Warning System, European Union, 2022
Substance Quantity material (kg)
3-CMC 19414.919
3-MMC 2848.907
2-MMC 1510.029
N-ethylnorpentedrone 1056.867
alpha-PHiP 568.344
Other 1123.861
Seizures of synthetic cathinones reported to the EU Early Warning System by country: numbers of seizures, European Union, 2022
Country Number of seizures
Austria 29
Belgium  
Bulgaria 1
Cyprus 1
Czechia 21
Germany 290
Denmark 17
Estonia 63
Greece 14
Spain 1416
Finland 472
France 778
Croatia 4
Hungary 888
Ireland  
Italy 51
Lithuania 66
Luxembourg 7
Latvia 56
Malta  
Netherlands 423
Poland 3398
Portugal 184
Romania 1
Sweden 1436
Slovenia 38
Slovakia 7
Seizures of synthetic cathinones reported to the EU Early Warning System by country: quantity of material seized for all forms reported in weight, European Union, 2022
Country Quantity material (kg)
Austria 2.125
Belgium 0
Bulgaria 0
Cyprus 0.001
Czechia 0.26
Germany 29.128
Denmark 0.04
Estonia 39.059
Greece 0.615
Spain 3455.04
Finland 9.229
France 0
Croatia 0.135
Hungary 138.554
Ireland 0
Italy 0.892
Lithuania 0.213
Luxembourg 0.082
Latvia 79.059
Malta 0
Netherlands 22249.65
Poland 299.515
Portugal 17.927
Romania 0.001
Sweden 200.056
Slovenia 1.098
Slovakia 0.248
Number of synthetic cannabinoids notified to the EU Early Warning System for the first time, European Union, 2005-2023
Year Cannabinoids
2008 1
2009 6
2010 11
2011 23
2012 31
2013 29
2014 30
2015 24
2016 11
2017 10
2018 11
2019 8
2020 11
2021 15
2022 22
2023 5
Seizures of synthetic cannabinoids reported to the EU Early Warning System: quantities of powders and herbal material seized, European Union, 2005-2022
Year 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Quantity herbal (kg)     2.58 87.75 118.53 71.26 173.51 206.56 1560.23 551.08 158.57 235.92 112.7 100.45 384.93 233.84
Quantity powder (kg)     2.03 41.11 20.76 323.52 595.41 419.12 337.09 191.1 149.95 70.77 82.6 96.7 57.4 504.06
Seizures of synthetic cannabinoids reported to the EU Early Warning System: trends in number of seizures, European Union, 2005-2022
Year 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Number of seizures 10 99 358 1006 1718 2820 9813 9601 7821 10003 8962 8729 6042 5714 6994 3441
Number of synthetic cannabinoids seized in the form of herbal material, European Union, 2022
Substance Number of seizures (herbal)
ADB-BUTINACA 1120
MDMB-4en-PINACA 339
CUMYL-NBMINACA 311
4F-MDMB-BICA 219
5F-MDMB-PICA 159
JWH-210 121
Other 788
Quantity of synthetic cannabinoids seized in the form of herbal material, European Union, 2022
Substance Quantity herbal (kg)
MDMB-4en-PINACA 90.9
ADB-BUTINACA 86.17
4F-ABINACA 9.81
JWH-210 7.13
4F-MDMB-BICA 6.71
CUMYL-CBMICA 6.36
Other 26.76
Number of synthetic cannabinoids seized in the form of powder, European Union, 2022
Substance Number of seizures (powder)
ADB-BUTINACA 100
MDMB-4en-PINACA 36
JWH-210 32
4F-MDMB-BICA 26
ADB-B-5Br-INACA 20
5F-MDMB-PICA 16
Other 154
Quantity of synthetic cannabinoids seized in the form of powder, European Union, 2022
Substance Quantity powder (kg)
JWH-210 460.22
ADB-BUTINACA 19.35
4F-MDMB-BICA 5.35
MDMB-4en-PINACA 4.83
5F-AKB48 1.6
ADB-5Br-INACA 1.48
Other 11.22
Seizures of synthetic cannabinoids reported to the EU Early Warning System by country: numbers of seizures, European Union, 2022
Country Number of cases
Austria 49
Bulgaria 988
Cyprus 3
Germany 974
Denmark 4
Estonia 1
Greece 15
Spain 44
Finland 20
France 479
Croatia 16
Hungary 375
Ireland 2
Italy 13
Lithuania 34
Luxembourg 5
Latvia 16
Montenegro 2
Netherlands 27
Poland 157
Portugal 30
Romania 6
Sweden 131
Slovenia 49
Slovakia 1
Seizures of synthetic cannabinoids reported to the EU Early Warning System by country: quantity of powder seized, European Union, 2022
Country name Quantity powder (kg)
Austria 0
Bulgaria 6.59
Cyprus 0
Germany 10.44
Denmark 0.04
Estonia 0
Greece 10.64
Spain 0.04
Finland 0.04
France 0
Croatia 0
Hungary 9.65
Ireland 0
Italy 0
Lithuania 1.37
Luxembourg 0
Latvia 0.42
Montenegro 0
Netherlands 462.86
Poland 1.04
Portugal 0
Romania 0.83
Sweden 0.11
Slovenia 0
Slovakia 0
Seizures of synthetic cannabinoids reported to the EU Early Warning System by country: quantity of herbal material seized, European Union, 2022
Country name Quantity herbal (kg)
Austria 12.48
Bulgaria 4.03
Cyprus 0
Germany 69.68
Denmark 0
Estonia 0
Greece 0.35
Spain 1.26
Finland 0.03
France 0
Croatia 0
Hungary 8.47
Ireland 0
Italy 0.84
Lithuania 0.51
Luxembourg 0
Latvia 0.03
Montenegro 0
Netherlands 68.38
Poland 2.87
Portugal 2
Romania 0.81
Sweden 57.49
Slovenia 4
Slovakia 0
Number of seizures of HHC (all forms) reported to the EU Early Warning System, European Union, 2022
Country name HHC seizures (all forms)
Austria 2
Bulgaria 4
Cyprus 1
Czechia 10
Germany 1
Denmark 5
Estonia 25
Greece 1
Spain 15
Finland 7
France 26
Croatia 1
Hungary 11
Italy 14
Lithuania 2
Poland 1
Sweden 8
Slovakia 2
Seizures of new opioids reported to the EU Early Warning System by country: numbers of seizures, European Union, 2022
Country Number of seizures
Austria 3
Belgium  
Bulgaria  
Cyprus  
Czechia  
Germany 14
Denmark 5
Estonia 88
Greece 20
Spain 25
Finland 49
France 14
Croatia  
Hungary 8
Ireland 2
Italy 2
Lithuania 248
Luxembourg  
Latvia 227
Malta  
Netherlands  
Poland 5
Portugal  
Romania  
Sweden 38
Slovenia 1
Slovakia  
Seizures of new opioids reported to the EU Early Warning System by country: quantity seized for all forms reported in weight, European Union, 2022
Country Quantity material (kg)
Austria 0.0508
Belgium 0
Bulgaria 0
Cyprus 0
Czechia 0
Germany 0.015489
Denmark 0.015
Estonia 1.163843
Greece 1.039
Spain 4.1163
Finland 0.0018
France 0
Croatia 0
Hungary 0.0028471
Ireland 0.0115
Italy 0.0082
Lithuania 6.579922406
Luxembourg 0
Latvia 2.88704
Malta 0
Netherlands 0
Poland 0.25839
Portugal 0
Romania 0
Sweden 0.444
Slovenia 0.00027
Slovakia 0
Top five new opioids seized by number of seizures reported to the EU Early Warning System, European Union, 2021
Substance Number of seizures
Carfentanil 335
Isotonitazene 160
Tramadol 166
ODT 14
Ocfentanil 10
Other opioids 55
Top five new opioids seized by number of seizures reported to the EU Early Warning System, European Union, 2022
Substance Number of seizures
Carfentanil 302
Tramadol 163
Protonitazene 104
Metonitazene 89
Isotonitazene 42
Other opioids 49
Top five new opioids seized by quantity seized reported to the EU Early Warning System, European Union, 2021
Substance Number of seizures
Carfentanil 4.884
Isotonitazene 1.917
Tramadol 0.282
ODT 0.143
U-49900 0.823
Other opioids 0.18
Top five new opioids seized by quantity seized reported to the EU Early Warning System, European Union, 2022
Substance Number of seizures
Carfentanil 8.243
Tramadol 5.201
Protonitazene 1.638
Metonitazene 0.873
Isotonitazene 0.267
Other opioids 0.372
Countries in Europe reporting identifications of nitazene opioids, 2019-2023 (all types of identification)
Country Count
Netherlands 1
Finland 1
Latvia 1
Ireland 1
Bulgaria 1
Austria 1
Hungary 1
Norway 1
Lithuania 1
Poland 1
Czechia 1
Estonia 1
Denmark 1
Italy 1
Slovenia 1
Sweden 1
Germany 1
France 1
Spain 1
Belgium 1
Portugal 1
Number of benzodiazepines reported for the first time in Europe, 2005-2023
Year Notifications
2005 0
2006 0
2007 1
2008 0
2009 0
2010 0
2011 1
2012 1
2013 2
2014 4
2015 5
2016 6
2017 3
2018 5
2019 2
2020 0
2021 3
2022 2
2023 1
Seizures of new benzodiazepines reported to the EU Early Warning System: number of seizures, European Union, 2022
Substance Number of seizures
Bromazolam 157
Etizolam 145
Flualprazolam 104
Flunitrazolam 63
Flubromazepam 50
Other 233
Seizures of new benzodiazepines reported to the EU Early Warning System: quantity seized for all forms reported in weight, European Union, 2022
Substance Quantity material (kg)
Etizolam 2.635
Flualprazolam 0.55
Deschloroetizolam 0.507
Bromazolam 0.299
Clonazolam 0.06
Other 0.152
Seizures of new benzodiazepines reported to the EU Early Warning System: quantity of tablets and capsules, European Union, 2022
Substance Tablets and capsules (units)
Flubromazolam 34488
Clonazolam 9829
Flualprazolam 8224.5
Flubromazepam 3572
Etizolam 3560
Other 10943.5
Seizures of new benzodiazepines reported to the EU Early Warning System by country: number of seizures, European Union, 2022
Country Number of seizures
Austria 14
Belgium  
Bulgaria  
Cyprus  
Czechia  
Germany 114
Denmark 36
Estonia 15
Greece 1
Spain 37
Finland 185
France 35
Croatia  
Hungary 8
Ireland 1
Italy 4
Lithuania 11
Luxembourg 8
Latvia 55
Malta  
Netherlands 34
Poland 16
Portugal  
Romania  
Sweden 173
Slovenia 2
Slovakia 3
Seizures of new benzodiazepines reported to the EU Early Warning System by country: quantity of material seized for all forms reported in weight, European Union, 2022
Country Quantity material (kg)
Austria 0.065
Belgium 0
Bulgaria 0
Cyprus 0
Czechia 0
Germany 0.216677
Denmark 0.2614
Estonia 0.05955
Greece 0
Spain 0.72436
Finland 0.09355
France 0
Croatia 0
Hungary 0.0019978
Ireland 0
Italy 0.002672
Lithuania 0.0490774
Luxembourg 0
Latvia 0.7943284
Malta 0
Netherlands 1.3967
Poland 0.25325
Portugal 0
Romania 0
Sweden 0.26342
Slovenia 0.02024
Slovakia 0.000339
Seizures of new benzodiazepines reported to the EU Early Warning System by country: quantity of tablets and capsules, European Union, 2022
Country Tablets and capsules (units)
Austria 0
Belgium 0
Bulgaria 0
Cyprus 0
Czechia 0
Germany 18051
Denmark 5660
Estonia 0
Greece 0
Spain 1972
Finland 3341.5
France 0
Croatia 0
Hungary 279.5
Ireland 0
Italy 0
Lithuania 0
Luxembourg 80
Latvia 548
Malta 0
Netherlands 489
Poland 200
Portugal 0
Romania 0
Sweden 39985
Slovenia 0
Slovakia 11
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