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Integrated approaches to improve engagement and adherence to HCV treatment among PWID
Summary of the evidence
Interventions aimed at improving engagement of PWID at any (or combination) of the following stages along the chronic HCV care cascade: a) linkage to care, defined as the clinical assessment of HCV infection or liver disease following diagnosis of HCV infection b) adherence to treatment, with regimens combining inter- feron/DAA or solely DAA were evaluated in a systematic review with meta-analysis (Schwarz et al., 2022, 14 studies).
Integrated care structures, where a variety of services are brought together, and nurse case management approaches that facilitate referral for HCV assessment and scheduling of specialist appointments for clients were found to be the most effective in:
- improving engagement throughout the continuum of HCV care among people who inject drugs and people receiving OST
Details
Note: this evidence summary is only valid for the outcomes, target groups, settings and substances/patterns of use described below.
